Founded in 2009, the Ontario Brain Institute (OBI) emerged to address fragmentation in Ontario's neuroscience research landscape. While the province boasted world-class labs and promising discoveries, they operated separately and with minimal coordination. Over more than a decade, OBI has united this expertise under a shared mission: driving innovation and impact across patient care, policy, and the economy through funding, capacity building, and strengthening networks. As a provincially funded non-profit, OBI has supported thousands of patients while catalyzing meaningful change in brain health. Today, OBI champions a "team science" approach that brings together researchers, clinicians, industry partners, patients, and advocates to strengthen existing treatments and create new pathways to care. Critically, OBI leverages digital innovation—from data platforms and analytics to virtual care tools—to accelerate discovery and scale solutions across the province. By challenging the status quo and fostering seamless digital and physical connections between research discovery, clinical practice, and commercialization, OBI operates as a learning healthcare system where knowledge flows freely among all stakeholders. This collaborative, digitally-enabled model amplifies impact—transforming scientific breakthroughs into tangible benefits for patients and positioning Ontario as a leader in brain health innovation.

Come and learn about holly™ , an OBI powered wearable-tech initiative—developed by Holland Bloorview Kids Rehabilitation Hospital, which uses real-time heart-rate and contextual data to map emotional arousal and drive next-gen neuro-tech solutions for mental-health and neurodevelopmental care