The global mental health crisis demands innovative approaches that combine scientific rigor with practical scalability. The Common Elements Treatment Approach (CETA), developed and refined over two decades at Johns Hopkins, represents such a breakthrough—a flexible, transdiagnostic system of care that effectively addresses multiple mental health conditions simultaneously through a streamlined model integrating assessment, treatment, and measurement-based monitoring. Evidence-Based and Globally Validated CETA's effectiveness has been demonstrated through rigorous testing in diverse settings across more than a dozen countries, such as Zambia, South Africa, Sierra Leone, Uganda, Myanmar, Iraq, Syria, and Ukraine. These implementations have often occurred in high-adversity contexts characterized by poverty, displacement, and violence—precisely where mental health resources are most scarce yet most needed. The model's efficiency is remarkable: requiring typically only 6-8 sessions while addressing comorbid conditions that would traditionally require multiple treatment protocols. This efficiency does not come at the expense of efficacy; multiple controlled trials demonstrate significant improvements in symptoms and functional outcomes. Democratizing Mental Health Care Through Task-Sharing Perhaps CETA's most transformative aspect is its proven effectiveness when delivered by trained lay providers through task-sharing approaches. This democratization of mental health care delivery has profound implications for addressing workforce shortages globally. By moving beyond the limitations of specialist-only models, CETA has demonstrated that quality mental health care can be made accessible even in contexts with minimal specialized workforce capacity. Digital Enhancement and AI Integration CETA has evolved to incorporate digital tools that support implementation at scale. These technologies enhance clinician and lay provider decision-making, ensure fidelity to the model, and enable real-time supervision and feedback. The approach is adaptable for both in-person and telehealth delivery, increasing its flexibility across contexts. Emerging applications integrate AI and machine learning to support triage processes, develop personalized care pathways, and identify risk factors across diverse populations. These innovations maintain the human-centered core of CETA while leveraging technology to extend reach and improve outcomes. A Disruptive Model for Global Mental Health By moving beyond diagnosis-driven silos and focusing instead on streamlining care delivery and effect outcomes, CETA offers a disruptive model for global mental health care. The approach has repeatedly demonstrated that quality, evidence-based treatment can be both scalable and contextually adaptable across cultural, socioeconomic, and geographic boundaries. This presentation will share quantitative outcomes from multiple global studies alongside practical implementation lessons from correctional systems, humanitarian settings, and community mental health programs. Attendees will gain actionable insights into transdiagnostic care delivery, task-sharing implementation, and the integration of digital tools to enhance mental health systems worldwide. CETA represents not merely a theoretical framework but a proven, implementable solution to one of our most pressing global health challenges—offering a bold path forward for transforming mental health care systems around the world.