Despite growing recognition of the effectiveness of digital mental health interventions, widespread integration into routine clinical care remains a global challenge. Most efforts to promote uptake are limited in scale, fragmented, or short-term. Australia’s e-Mental Health in Practice (eMHPrac) initiative stands as an internationally unique and enduring example of national implementation in primary care, combining clinician education, systemic change, and policy engagement over more than a decade. Funded by the Australian Government and operating since 2013, eMHPrac is a national consortium that has delivered large-scale, multi-modal training and implementation support to general practitioners, allied health professionals, and Indigenous health workers. Activities include face-to-face and online workshops, webinars, awareness presentations, interactive modules, a directory of evidence-based digital services and tools, and widely distributed guides. Engagement is tailored to professional roles and settings, with culturally safe resources delivered through the WellMob portal for Aboriginal and Torres Strait Islander communities. eMHPrac has also contributed to national digital health strategy and has helped shape safety and quality standards. To date, eMHPrac has delivered over 2,200 training activities to more than 87,000 health practitioners to support the integration of digital tools into practice. More than 225,000 guides, brochures, and fact sheets have been distributed in print and digital format. Since 2021, over 130,000 practitioners have accessed eMHPrac’s podcasts, newsletters, and blogs, and the website continues to attract 8,000 sessions per month. This reach has been enabled by multiple access points tailored to the needs of busy clinicians, offering low-burden, practical training options that support real-world implementation. Critically, eMHPrac has contributed to a 202% increase in practitioner referrals to major Australian digital mental health services, alongside a 151% rise in user registrations over the past decade. What sets eMHPrac apart is not only its national scale and sustained delivery, but its strategic alignment with policy, its tailoring to diverse professional roles, and its integration of digital mental health into workforce development. Its success demonstrates the importance of sustained cross-sector collaboration and the strategic cultivation of digital champions to drive change. Future directions include expanding training offerings to the broader health workforce, increasing organizational change support, and advocating for system-level reforms. In a global context where many countries still grapple with how to translate digital mental health innovation into routine care, eMHPrac offers a rare, replicable and cost-effective blueprint. It demonstrates that with coordinated investment, practitioner engagement, and policy alignment, digital mental health can move from peripheral innovation to a core component of mental healthcare delivery.